Concepedia

Rat Adipose Tissue-Derived Stem Cells Transplantation Attenuates Cardiac Dysfunction Post Infarction and Biopolymers Enhance Cell Retention

Maria Elena Danoviz, Juliana Sanajotti Nakamuta, Fábio Luiz Navarro Marques, Leonardo dos Santos, Alexandra Alberta dos Santos, Ednei Luiz Antônio, Isolmar Tadeu Schettert, Paulo José Ferreira Tucci, José Eduardo Krieger

PLoS ONE · 2010 · 118 citations · 42 references

DOIFull text

Open access

Abstract

We provided direct evidence that intramyocardial injection of ASCs mitigates the negative cardiac remodeling and preserves ventricular function post-MI in rats and these beneficial effects can be further enhanced by administering co-injection of ASCs with biopolymers.

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