Krüppel-like factor 1 mutations and expression of hemoglobins F and A2 in homozygous hemoglobin E syndrome

Genome-wide association study shows <i>BCL11A</i> associated with persistent fetal hemoglobin and amelioration of the phenotype of β-thalassemia

Manuela Uda, Renzo Galanello, Serena Sanna et al. · Proceedings of the National Academy of Sciences · 2008 · 655 citations · Full text

Immunohematology, Genetics, Bcl11a Gene +19

Haploinsufficiency for the erythroid transcription factor KLF1 causes hereditary persistence of fetal hemoglobin

Joseph Borg, Petros Papadopoulos, Marianthi Georgitsi et al. · Nature Genetics · 2010 · 369 citations · Full text

Transcriptional Regulation, Developmental Biology, Heme Homeostasis +9

KLF1 regulates BCL11A expression and γ- to β-globin gene switching

Dewang Zhou, Kaimao Liu, Chiao‐Wang Sun et al. · Nature Genetics · 2010 · 356 citations

Transcriptional Regulation, Signal Transduction, Bcl11a Expression +10

A Dominant Mutation in the Gene Encoding the Erythroid Transcription Factor KLF1 Causes a Congenital Dyserythropoietic Anemia

Lionel Arnaud, Carole Saison, Virginie Helias et al. · The American Journal of Human Genetics · 2010 · 196 citations · Full text

Transcriptional Regulation, Developmental Biology, Genetic Disorder +10

Mutations in EKLF/KLF1 form the molecular basis of the rare blood group In(Lu) phenotype

Belinda K. Singleton, Nicholas M. Burton, Carole Green et al. · Blood · 2008 · 166 citations