Uncoupling of genomic instability and tumorigenesis in a mouse model of Burkitt's lymphoma expressing a conditional box II-deleted Myc protein

Hypermutation of multiple proto-oncogenes in B-cell diffuse large-cell lymphomas

Laura Pasqualucci, Peter Neumeister, Tina Goossens et al. · Nature · 2001 · 1K citations

Medicine, Genetics, Molecular Genetics +13

A modified oestrogen receptor ligand-binding domain as an improved switch for the regulation of heterologous proteins

Trevor D. Littlewood, David C. Hancock, Paul S. Danielian et al. · Nucleic Acids Research · 1995 · 789 citations · Full text

Life Sciences, Biochemistry, Endocrinology +16

Definition of regions in human c-myc that are involved in transformation and nuclear localization.

James C. Stone, Titia de Lange, Gary Ramsay et al. · Molecular and Cellular Biology · 1987 · 455 citations · Full text

Medicine, Genetics, Molecular Biology +17

c‐Myc represses transcription in vivo by a novel mechanism dependent on the initiator element and Myc box II.

Linheng Li, Claus Nerlov, George C. Prendergast et al. · The EMBO Journal · 1994 · 312 citations · Full text

Life Sciences, Genetics, Molecular Biology +13

Point mutations in the c–Myc transactivation domain are common in Burkitt's lymphoma and mouse plasmacytomas

Karishma Bhatia, Konrad Hüppi, G Spangler et al. · Nature Genetics · 1993 · 288 citations

Medicine, Molecular Genetics, Oncology +16