Novel fibroblast growth factor receptor 3 (FGFR3) mutations in bladder cancer previously identified in non-lethal skeletal disorders

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

Rita Shiang, Leslie M. Thompson, Yazhen Zhu et al. · Cell · 1994 · 1.3K citations

Biology, Mendelian Disorder, Genetic Disorder +8

Mutations in the gene encoding fibroblast growth factor receptor-3 in achondroplasia

Francis Rousseau, Jacky Bonaventure, Laurence Legeai‐Mallet et al. · Nature · 1994 · 928 citations

Fibrosis, Genetic Disorder, Genetics +5

Frequent activating mutations of FGFR3 in human bladder and cervix carcinomas

David Cappellen, Catherine De Oliveira, David Ricol et al. · Nature Genetics · 1999 · 701 citations

Tumor Biology, Human Bladder, Urology +9

Frequent translocation t(4;14)(p16.3;q32.3) in multiple myeloma is associated with increased expression and activating mutations of fibroblast growth factor receptor 3

Marta Chesi, Elena Nardini, Leslie A. Brents et al. · Nature Genetics · 1997 · 646 citations · Full text

Hematological Malignancy, Frequent Translocation T, Immunology +8

Thanatophoric dysplasia (types I and II) caused by distinct mutations in fibroblast growth factor receptor 3

Patricia L. Tavormina, Rita Shiang, Leslie M. Thompson et al. · Nature Genetics · 1995 · 605 citations

Thanatophoric Dysplasia, Fibrosis, Mendelian Disorder +8