Leslie M. Thompson

Mutations in the transmembrane domain of FGFR3 cause the most common genetic form of dwarfism, achondroplasia

Rita Shiang, Leslie M. Thompson, Yazhen Zhu et al. · Cell · 1994 · 1.3K citations

Life Sciences, Genetics, Molecular Genetics +13

Histone deacetylase inhibitors arrest polyglutamine-dependent neurodegeneration in Drosophila

Joan S. Steffan, László Bodai, Judit Pallos et al. · Nature · 2001 · 1.2K citations · Full text

Life Sciences, Molecular Biology, Neuroscience +14

The Huntington's disease protein interacts with p53 and CREB-binding protein and represses transcription

Joan S. Steffan, Aleksey Kazantsev, Olivera Spasić-Bošković et al. · Proceedings of the National Academy of Sciences · 2000 · 1.1K citations

Life Sciences, Genetics, Molecular Biology +17

Suberoylanilide hydroxamic acid, a histone deacetylase inhibitor, ameliorates motor deficits in a mouse model of Huntington's disease

Emma Hockly, Victoria M. Richon, Benjamin Woodman et al. · Proceedings of the National Academy of Sciences · 2003 · 841 citations · Full text

Life Sciences, Neuroscience, Pharmacology +17

SUMO Modification of Huntingtin and Huntington's Disease Pathology

Joan S. Steffan, Namita Agrawal, Judit Pallos et al. · Science · 2004 · 709 citations · Full text

Life Sciences, Genetics, Molecular Biology +16