Ultrastructural study of the pacinian corpuscles in the newborn and adult dog forefoot

Abstract

Pacinian corpuscles (PC) of the newborn and adult dog forefoot were studied by electron microscopy. The PC of newborn dog forefoot show a rare development: they exhibit a lamellar arrangement, although the lamellar compartments do not surround completely the fiber. The outer core cells show a well-developed perinuclear endoplasmic reticulum. They are surrounded by a discontinuous basal lamina. Mast cells between the lamellae of the outer core are observed. Desmosome-like and zonula adherens junctions, as well as pinocytotic vesicles, are shown in the inner core cells. Intermediate filaments are also observed in the glial cells of the inner core. In PC of adult dog forefoot a general organization of a concentrically arranged capsule, outer core, intermediate layer and inner core around a nerve ending is always present. In the intermediate layer, lamellar cells (specialized fibroblast) do not surround completely the inner core. The inner core lamellae possess numerous pinocytotic vesicles, an extensive network of filaments, special cell junctions (gap, desmosome) and a discontinuous basal lamina. The present results show a conservative structural organization in PC, although differences among species are discussed.