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MILD, essential hypertension has been defined as the "gray zone" between normal BP and essential hypertension that clearly warrants treatment.<sup>1</sup>While many agree that in adults diastolic BP (DBP) below 90 mm Hg is "normal," this upper limit is artificial. The Framingham study has been interpreted as showing a linear relationship between the subsequent development of cardiovascular disease and baseline DBP over 60 mm Hg<sup>2</sup>(although this interpretation has been disputed).<sup>3</sup>Normal DBP depends on age, sex, and race; but the use of 90 mm Hg as the universal upper limit of normotension seems safe and utilitarian. Defining the lower limit of DBP that clearly demands treatment is even more difficult. The Joint National Committee on Detection, Evaluation, and Treatment of High Blood Pressure recommends that all patients with a DBP of 105 mm Hg or greater be treated.<sup>4</sup>The clinical effectiveness of treating such patients was shown
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The Australian therapeutic trial in mild hypertension.
John Abernethy · Hypertension · 1984 · 529 citations · Full text