Thomas C. Chalmers

The Importance of Beta, the Type II Error and Sample Size in the Design and Interpretation of the Randomized Control Trial

Jennie A. Freiman, Thomas C. Chalmers, Harry Smith et al. · New England Journal of Medicine · 1978 · 1.6K citations

Public Health, Biostatistics, Experimental Design +16

A method for assessing the quality of a randomized control trial

Thomas C. Chalmers, Harry Smith, Bradley A. Blackburn et al. · Controlled Clinical Trials · 1981 · 1.4K citations

Public Health, Biostatistics, Evidence-based Practice +10

Meta-Analyses of Randomized Controlled Trials

Henry S. Sacks, Jayne Berrier, Dinah Reitman et al. · New England Journal of Medicine · 1987 · 1.3K citations

Public Health, Biostatistics, Comparative Effectiveness Research +8

Cumulative Meta-Analysis of Therapeutic Trials for Myocardial Infarction

Joseph Lau, Elliott M. Antman, Jeanette Jimenez-Silva et al. · New England Journal of Medicine · 1992 · 1.2K citations · Full text

Medicine, Biostatistics, Cardiology +16

Appraisal of methods for the study of chemotherapy of cancer in man: Comparative therapeutic trial of nitrogen mustard and triethylene thiophosphoramide

C. Gordon Zubrod, Marvin A. Schneiderman, Emil Frei et al. · Journal of Chronic Diseases · 1960 · 1K citations

Medicine, Oncology, Chemotherapy +4