Effects of baicalein, a flavonoid, and other anti-inflammatory agents on glyoxalase-I activity.

Abstract

Flavonoids, widely distributed in edible plants, have various biochemical and physiological activities1 ~3) including an anti-inflammatory effect.4) In a previous article, we showed that flavonoids such as quercetin and fisetin are potent inhibitors of glyoxalase-I5) [S-lactoylglutathione methylglyoxal-lyase (isomerizing) EC 4.4. 1.5]. It was pro: