Anxiogenic effects in benzodiazepine withdrawal are linked to the development of tolerance

Validation of open : closed arm entries in an elevated plus-maze as a measure of anxiety in the rat

Sharon Pellow, Philippe Chopin, Sandra E. File et al. · Journal of Neuroscience Methods · 1985 · 5.8K citations

Social Sciences, Behavioral Sciences, Psychology +9

Anxiolytic and anxiogenic drug effects on exploratory activity in an elevated plus-maze: A novel test of anxiety in the rat

Sharon Pellow, Sandra E. File · Pharmacology Biochemistry and Behavior · 1986 · 1.5K citations

Medicine, Neuroscience, Pharmacology +13

The use of social interaction as a method for detecting anxiolytic activity of chlordiazepoxide-like drugs

Sandra E. File · Journal of Neuroscience Methods · 1980 · 818 citations

Medicine, Pharmacology, Behavioral Pharmacology +5

Withdrawal reactions from chlordiazepoxide (?Librium?)

Leo E. Hollister, Francis P. Motzenbecker, Roger O. Degan · Psychopharmacology · 1961 · 344 citations

Medicine, Pharmacology, Pharmacotherapy +9

Behavior analysis of the effects and mechanisms of action of benzodiazepines.

Gál Em · PubMed · 1974 · 237 citations

Medicine, Pharmacology, Psychiatry +17