Novel T-type calcium channel blockers: Dioxoquinazoline carboxamide derivatives

Silencing of the Cav3.2 T‐type calcium channel gene in sensory neurons demonstrates its major role in nociception

Emmanuel Bourinet, Abdelkrim Alloui, Arnaud Monteil et al. · The EMBO Journal · 2004 · 443 citations · Full text

Life Sciences, Neurobiology, Neuroscience +16

Discovery of the Novel Antithrombotic Agent 5-Chloro-<i>N</i>-({(5<i>S</i>)-2-oxo-3- [4-(3-oxomorpholin-4-yl)phenyl]-1,3-oxazolidin-5-yl}methyl)thiophene- 2-carboxamide (BAY 59-7939):  An Oral, Direct Factor Xa Inhibitor

Susanne Roehrig, Alexander Straub, Jens Pohlmann et al. · Journal of Medicinal Chemistry · 2005 · 433 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +10

Abnormal Coronary Function in Mice Deficient in α _1H T-type Ca ²⁺ Channels

Chien‐Chang Chen, Kathryn G. Lamping, Daniel W. Nuno et al. · Science · 2003 · 331 citations

Life Sciences, Cardiology, Physiology +17

Thalamic Control of Visceral Nociception Mediated by T-Type Ca ²⁺ Channels

Daesoo Kim, Donghyun Park, Soonwook Choi et al. · Science · 2003 · 225 citations

Life Sciences, Neurobiology, Neuroscience +17

Synthesis and Evaluation of a New Class of Nifedipine Analogs with T-Type Calcium Channel Blocking Activity

P. Phani Kumar, Stephanie C. Stotz, R. Paramashivappa et al. · Molecular Pharmacology · 2002 · 84 citations

Medicine, Medicinal Chemistry, Pharmacology +16