Concepedia

Eco-friendly polyethylene glycol-400: a rapid and efficient recyclable reaction medium for the synthesis of thiazole derivatives

Bhaskar S. Dawane, Baseer M. Shaikh, Namdev T. Khandare, Vinod T. Kamble, Santosh S. Chobe, Shankaraiah G. Konda

Green Chemistry Letters and Reviews · 2010 · 33 citations · 13 references

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Abstract

Abstract An efficient and convenient procedure for the synthesis of thiazole derivatives from α-haloketone, thiourea and substituted acetophenones using polyethylene glycol-400 as a green and recyclable solvent is described. Significant rate enhancement and improved yields have been observed.

References

13

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Phenethylthiazolethiourea (PETT) Compounds, a New Class of HIV-1 Reverse Transcriptase Inhibitors. 1. Synthesis and Basic Structure-Activity Relationship Studies of PETT Analogs

Frank W. Bell, Amanda Cantrell, Marita Hoegberg et al. · Journal of Medicinal Chemistry · 1995 · 455 citations · Full text

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Structure-activity relationships of a series of 2-amino-4-thiazole-containing renin inhibitors

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4-(1,2,5,6-Tetrahydro-1-alkyl-3-pyridinyl)-2-thiazolamines: a novel class of compounds with central dopamine agonist properties

Juan C. Jaén, Lawrence D. Wise, Bradley W. Caprathe et al. · Journal of Medicinal Chemistry · 1990 · 255 citations · Full text

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