Excess of De Novo Deleterious Mutations in Genes Associated with Glutamatergic Systems in Nonsyndromic Intellectual Disability

A map of human genome variation from population-scale sequencing

Nature · 2010 · 8.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

The SWISS-MODEL workspace: a web-based environment for protein structure homology modelling

Konstantin Arnold, Lorenza Bordoli, Jürgen Kopp et al. · Bioinformatics · 2005 · 7.1K citations · Full text

Life Sciences, Biochemistry, Bioinformatics +12

SIFT: predicting amino acid changes that affect protein function

P.C. Ng · Nucleic Acids Research · 2003 · 6.9K citations · Full text

Life Sciences, Bioinformatics, Genetics +17

Mutations in the gene encoding the synaptic scaffolding protein SHANK3 are associated with autism spectrum disorders

Christelle M. Durand, Catalina Betancur, Tobias M. Boeckers et al. · Nature Genetics · 2006 · 1.6K citations · Full text

Life Sciences, Genetics, Neuroscience +12

Protein structure homology modeling using SWISS-MODEL workspace

Lorenza Bordoli, Florian Kiefer, Konstantin Arnold et al. · Nature Protocols · 2008 · 1.3K citations

Life Sciences, Biochemistry, Bioinformatics +10