Cytochrome P-450 mRNA Expression in Human Liver and Its Relationship with Enzyme Activity

Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

Medicine, Biochemistry, Pharmacology +15

Ethoxy-, pentoxy- and benzyloxyphenoxazones and homologues: a series of substrates to distinguish between different induced cytochromes P-450

M.D. Burke, S. Thompson, Clifford R. Elcombe et al. · Biochemical Pharmacology · 1985 · 1.3K citations

Medicine, Pharmacology, Drug Metabolism +8

Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P-450IIE1

Raimund M. Peter, Ronald Boecker, Philippe Beaune et al. · Chemical Research in Toxicology · 1990 · 535 citations

Medicine, Pharmacology, Toxicology +11

Complementary DNA and protein sequences of ethanol-inducible rat and human cytochrome P-450s. Transcriptional and post-transcriptional regulation of the rat enzyme.

Byoung‐Joon Song, Harry V. Gelboin, S S Park et al. · Journal of Biological Chemistry · 1986 · 409 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +13

Nomenclature for human CYP2D6 alleles

Ann K. Daly, Jürgen Brockmöller, Franck Broly et al. · Pharmacogenetics · 1996 · 400 citations

Life Sciences, Genetics, Molecular Genetics +13