Bioconductor: open software development for computational biology and bioinformatics

Robert Gentleman, Vincent J. Carey, Douglas M. Bates, +22

Genome biology

CpG island methylator phenotype in colorectal cancer

Minoru Toyota, Nita Ahuja, Mutsumi Ohe-Toyota, +3

Proceedings of the National Academy of Sciences

Tumor BiologyAberrant MethylationMedicineGeneticsEpigenetic Change +10

Tumor Microsatellite-Instability Status as a Predictor of Benefit from Fluorouracil-Based Adjuvant Chemotherapy for Colon Cancer

Christine Ribic, Daniel J. Sargent, Malcolm J. Moore, +10

New England Journal of Medicine

High-frequency Microsatellite InstabilityImmunologyAdjuvant ChemotherapyPathologyTumor Biology +14

Tumor Microsatellite Instability and Clinical Outcome in Young Patients with Colorectal Cancer

Robert Gryfe, Hyeja Kim, Eugene Hsieh, +5

New England Journal of Medicine

Somatic Frameshift Mutations in the <i>BAX</i> Gene in Colon Cancers of the Microsatellite Mutator Phenotype

Nicholas J. Rampino, Hiroyuki Yamamoto, Yurij Ionov, +3

Science

DNMT1 and DNMT3b cooperate to silence genes in human cancer cells

Ina Rhee, Kurtis E. Bachman, Ben Ho Park, +9

Nature

ChromatinTumor BiologyCell RegulationMedicineCancer Genetics +6

Hypermethylation of the hMLH1 promoter in colon cancer with microsatellite instability.

Julie M. Cunningham, Eric R. Christensen, David J. Tester, +4

PubMed

GeneticsPathologyHmlh1 PromoterCancer BiologyWidespread Msi +15

Clinical and pathological characteristics of sporadic colorectal carcinomas with DNA replication errors in microsatellite sequences.

Hoguen Kim, Jin Jen, Bert Vogelstein, +1

PubMed

Villin is a major protein of the microvillus cystoskeleton which binds both G and F actin in a calcium-dependent manner

Anthony Bretscher, Klaus Weber

Cell

Microvillus CystoskeletonProtein FunctionMolecular PhysiologySignal TransductionMajor Protein +10

Microsatellite instability in sporadic colon cancer is associated with an improved prognosis at the population level.

Wade S. Samowitz, Karen Curtin, Donna Schaffer, +3

PubMed

OncologyCancer PathologyImproved PrognosisGastrointestinal OncologyMedicine +12