Preoperative Imaging of Abnormal Parathyroid Glands in Patients with Hyperparathyroid Disease Using Combination Tc-99m-Pertechnetate and Tc-99m-Sestamibi Radionuclide Scans

Abstract

Tc-99m-pertechnetate combined with Tc-99m-sestamibi subtraction radionuclide scanning is less cumbersome to implement than iodine-123 combined with Tc-99m-sestamibi scanning. It has a high sensitivity for imaging solitary parathyroid adenomas or persistent solitary hyperplastic glands. However it does not have the resolution necessary to delineate all parathyroid glands in diffuse hyperplasia.