PLoS ONE · 2013 · 18 citations · 35 references
Veterinary MedicineEconomicsHealth SciencesForecastingTemporal EpidemiologyTime Series AnalysisCardiovascular DiseaseCardiovascular EpidemiologyCardiovascular RiskMortality AnalysisMortality PatternsTime-series Analysis In EpidemiologyAutoregressive Distributed Lag ModelsCardiovascular Disease MortalityConfoundingDelay EffectsDistributed Lag ModelsRelative Risk EstimationTemporal Trends In Mortality
OBJECTIVE: The current study aimed to examine the effects of daily change of the Shenzhen Stock Exchange Index on cardiovascular mortality in Guangzhou and Taishan, China. METHODS: Daily mortality and stock performance data during 2006-2010 were collected to construct the time series for the two cities. A distributed lag non-linear model was utilized to examine the effect of daily stock index changes on cardiovascular mortality after controlling for potential confounding factors. RESULTS: We observed a delayed non-linear effect of the stock index change on cardiovascular mortality: both rising and declining of the stock index were associated with increased cardiovascular deaths. In Guangzhou, the 15-25 lag days cumulative relative risk of an 800 index drop was 2.08 (95% CI: 1.38-3.14), and 2.38 (95% CI: 1.31-4.31) for an 800 stock index increase on the cardiovascular mortality, respectively. In Taishan, the cumulative relative risk over 15-25 days lag was 1.65 (95% CI: 1.13-2.42) for an 800 index drop and 2.08 (95% CI: 1.26-3.42) for an 800 index rising, respectively. CONCLUSIONS: Large ups and downs in daily stock index might be important predictor of cardiovascular mortality.
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