International journal of peptide & protein research · 1985 · 65 citations · 16 references
MedicineBiochemistryNephrologyDialysisHemodialysisRenal Replacement TherapyAmino Acid CompositionAmino Acid MetabolismChromatographyChronic HemodialysisDialysate CompositionLiquid ChromatographyAlbumin Analysis In Body FluidsAmino AcidsAnalytical Liquid ChromatographyChronic Renal InsufficiencyMercapturic Acid FormationPlasma AlbuminProtein Carrier Systems
Human mercaptalbumin (HMA) and nonmercaptalbumin (HNA) could be separated by high-performance liquid chromatography (HPLC) at neutral pH. Using HPLC, the present authors found the nonmercapt-mercapt conversion (HNA----HMA) during hemodialysis and the mercapt-nonmercapt conversion (HMA----HNA) after hemodialysis in chronic renal failure, indicating HMA as the covalent carrier protein for sulfur-containing amino acids.
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