Posttraumatic Lipoma: Fact or Fiction?

Abstract

The pathogenetic link between soft tissue trauma and the formation of posttraumatic lipomas is still controversially discussed. There are 2 potential explanations to correlate soft tissue trauma and adipose tissue tumor growth. The first is the formation of so-called posttraumatic pseudolipomas by prolapsing adipose tissue through fascia resulting from direct impact. A second possibility points toward lipoma formation as a result of preadipocyte differentiation and proliferation mediated by cytokine release following soft tissue trauma and hematoma formation.