Probabilistic drug connectivity mapping

Gene set enrichment analysis: A knowledge-based approach for interpreting genome-wide expression profiles

Aravind Subramanian, Pablo Tamayo, Vamsi K. Mootha et al. · Proceedings of the National Academy of Sciences · 2005 · 54.5K citations · Full text

Genetics, Genomics, Gene Recognition +23

The Connectivity Map: Using Gene-Expression Signatures to Connect Small Molecules, Genes, and Disease

Justin Lamb, Emily Crawford, D. D. Peck et al. · Science · 2006 · 5.4K citations

Genetics, Molecular Biology, Biological Network +19

RELATIONS BETWEEN TWO SETS OF VARIATES

Harold Hotelling · Biometrika · 1936 · 5.4K citations

Literary Theory, Humanities, Literary Criticism +7

Summaries of Affymetrix GeneChip probe level data

Rafael A. Irizarry · Nucleic Acids Research · 2003 · 4.9K citations · Full text

Predicting new molecular targets for known drugs

Michael J. Keiser, Vincent Setola, John J. Irwin et al. · Nature · 2009 · 1.7K citations · Full text

Medicinal Chemistry, Drug Target, New Molecular Targets +6