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Lead optimization at C-2 and N-3 positions of thiazolidin-4-ones as HIV-1 non-nucleoside reverse transcriptase inhibitors

Medicinal ChemistryBiochemistryMedicineNatural SciencesRational Drug DesignAntiviral Drug DevelopmentResistance Mutation (Virology)Lead IdentificationHivChemical BiologyPharmacologyAntiviral CompoundN-3 PositionsDrug DiscoveryLead Optimization