Concepedia

Publication | Open Access

AVX-470

DOIFull Paper Access

62

Citations

20

References

2013

Year

Kailash C. Bhol, Daniel E. Tracey, Brenda Lemos, Gregory D. Lyng, Emma Erlich, David M. Keane, Michael S. Quesenberry, Amy D. Holdorf, Lisa D. Schlehuber, Shawn Clark,
Inflammatory Bowel Diseases

Abstract

AVX-470 is a novel polyclonal anti-TNF antibody with an in vitro activity profile comparable to that of infliximab. Oral administration of a surrogate antibody specific for mouse TNF is effective in treating mouse models of IBD, delivering the anti-TNF to the site of inflammation with minimal systemic exposure.

References

YearCitations

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