Budd-Chiari syndrome after taking oral contraceptives.

Abstract

This is the case study of a 28-year-old housewife admitted to the hospital on December 20 1966. She had been on oral contraceptives (Lyndiol) for 12-18 months until December 12 when they were stopped due to increased nausea. The womans health until this time had been excellent. On admission she was found to have a distended liver 8-10 cm below the right rib margin elevated diaphram enlarged spleen ascites and several small lymph nodes in the side of the neck. Her condition continued to deteriorate and she died on March 14 1966 after repeated hemorrhages from the Budd-Chari syndrome (hepatic vein thrombosis) which was determined from necropsy report. This syndrome is more common in men than women but needs to be evaluated further in women receiving oral contraceptives.