Concepedia

Gamma secretase inhibitor blocks Notch activation and induces apoptosis in Kaposi's sarcoma tumor cells

Christine L. Curry, Laura L Reed, Todd E. Golde, Lucio Miele, Brian J. Nickoloff, Kimberly E. Foreman

Oncogene · 2005 · 212 citations · 39 references

DOI

Concepts

References

39

Activating Mutations of <i>NOTCH1</i> in Human T Cell Acute Lymphoblastic Leukemia

Andrew P. Weng, Adolfo A. Ferrando, Woojoong Lee et al. · Science · 2004 · 2.7K citations

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TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms

Leif W. Ellisen, Daniel C. West, A. Lee Soreng et al. · Cell · 1991 · 1.7K citations

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Signalling downstream of activated mammalian Notch

Sophie Jarriault, Christel Brou, Frédérique Logeat et al. · Nature · 1995 · 1.4K citations

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Notch1 functions as a tumor suppressor in mouse skin

Michaël Nicolas, Anita Wolfer, Kenneth Raj et al. · Nature Genetics · 2003 · 972 citations · Full text

, , +11

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

Annapoorni Rangarajan, Claudio Talora, Ryuhei Okuyama et al. · The EMBO Journal · 2001 · 860 citations · Full text

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