Electro-oculogram findings in patients treated with antimalarial drugs.

Abstract

WITHIN the last few years it has become increasingly evident that the antimalarial drugs cause eye damage. First developed as a cure for malaria, these drugs are now widely used in the treatment of the chronic collagenoses for which the dosages are very large and may be prolonged for many years. In this time the drugs accumulate in the body and reach toxic levels. This often results in severe visual disturbances. Corneal deposits of the drugs may temporarily impair the optical properties of the eye, but are of minor importance as they are easily reversible when drug treatment ceases (Hobbs and