Amyloid-binding compounds maintain protein homeostasis during ageing and extend lifespan

Genes that act downstream of DAF-16 to influence the lifespan of Caenorhabditis elegans

Coleen T. Murphy, Steven A. McCarroll, Cornelia I. Bargmann et al. · Nature · 2003 · 2.3K citations

Education, Genetics, Molecular Genetics +11

Ingestion of bacterially expressed dsRNAs can produce specific and potent genetic interference in Caenorhabditis elegans

Lisa Timmons, Donald L. Court, Andrew Fire · Gene · 2001 · 1.9K citations

Life Sciences, Biology, Genetics +9

Regulation of Aging and Age-Related Disease by DAF-16 and Heat-Shock Factor

Ao‐Lin Hsu, Coleen T. Murphy, Cynthia Kenyon · Science · 2003 · 1.5K citations

Education, Genetics, Molecular Biology +17

The genetics of caloric restriction in <i>Caenorhabditis elegans</i>

Bernard Lakowski, Siegfried Hekimi · Proceedings of the National Academy of Sciences · 1998 · 984 citations · Full text

Life Sciences, Biology, Genetics +13

Direct Inhibition of the Longevity-Promoting Factor SKN-1 by Insulin-like Signaling in C. elegans

Jennifer M. A. Tullet, Maren Hertweck, Jae Hyung An et al. · Cell · 2008 · 931 citations · Full text

Life Sciences, Biology, Molecular Biology +13