Chemical Constituents of Crotalaria madurensis

Abstract

Two new compounds, crotmadine (1) and crotmarine (3); a known pyrrolizidine alkaloid, fulvine (8), and three other known compounds, trans-3,4,3',5'-tetra methoxystilbene (5), dihydroalpinumisoflavone (6), and 4',5,7-trihydroxy-3-methoxyflavone (7), have been isolated from the leaves and stems of Crotalaria madurensis. Both crotmadine (1) and crotmarine (3) exhibit antifungal activity against Trichophyton mentagrophytes.