Concepedia

Metabolomics-Based Discovery of Diagnostic Biomarkers for Onchocerciasis

Judith R. Denery, Ashlee A. K. Nunes, Mark S. Hixon, Tobin J. Dickerson, Kim D. Janda

PLoS neglected tropical diseases · 2010 · 81 citations · 35 references

DOIFull text

Open access

Abstract

An LC-MS metabolomics-based diagnostic has the potential to monitor the progression of onchocerciasis in both endemic and non-endemic geographic areas, as well as provide an essential tool to multinational programs in the ongoing fight against this neglected tropical disease. Ultimately this technology can be expanded for the diagnosis of other filarial and/or neglected tropical diseases.

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