Transition‐Metal‐Mediated Routes to 3,3‐Disubstituted Oxindoles through Anilide Cyclisation

Abstract

Abstract This review describes transition‐metal‐catalysed and ‐mediated processes for the preparation of oxindoles from anilides through C(3)–C(3a) bond formation. Traditional methods, such as the Heck reaction, and recent developments, including direct Ar–H coupling processes, are presented, as are applications in natural product synthesis.