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Synthesis and Antifungal Activity of Cinnamic Acid Esters
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1996
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Antifungal AgentAnanas Comosus VarPineapple StemsBotanyMedicineFerulic AcidsPhytochemicalMicrobiologyPhytochemistryPharmacologyCinnamic Acid EstersNatural Product Synthesis
Cinnamic, p-coumaric and ferulic acids were isolated from pineapple stems (Ananas comosus var. Cayenne). Twenty-four kinds of esters were prepared from these acids, alcohols and the components of Alpinia. Isopropyl 4-hydroxycinnamate (11) and butyl 4-hydroxycinnamate (12) were found to have almost the same effectiveness in antifungal activity against Pythium sp. at 10 ppm as that of the commercial fungicide iprobenfos (kitazin P).