Evidence for involvement of both D1 and D2 receptors in maintaining cocaine self-administration

Opposing roles for D-1 and D-2 dopamine receptors in efflux of cyclic AMP from rat neostriatum

J.C. Stoof, John W. Kebabian · Nature · 1981 · 917 citations

Life Sciences, Neurobiology, Neuroscience +16

Molecular pharmacology of 5-HT1 and 5-HT2 recognition sites in rat and pig brain membranes: Radioligand binding studies with [3H]5-HT, [3H]8-OH-DPAT, (−)[125I]iodocyanopindolol, [3H]mesulergine and [3H]Ketanserin

Daniël Hoyer, G. Engel, Hans O. Kalkman · European Journal of Pharmacology · 1985 · 577 citations

Life Sciences, Neuroscience, Pharmacology +13

Blockade of cocaine reinforcement in rats with the dopamine receptor blocker pimozide, but not with the noradrenergic blockers phentolamine or phenoxybenzamine.

Harriet de Wit, Roy A. Wise · Canadian Journal of Psychology/Revue Canadienne de Psychologie · 1977 · 494 citations

Medicine, Neuroscience, Pharmacology +16

COCAINE-REINFORCED BEHAVIOR IN RATS: EFFECTS OF REINFORCEMENT MAGNITUDE AND FIXED-RATIO SIZE

Roy W. Pickens, Travis Thompson · Journal of Pharmacology and Experimental Therapeutics · 1968 · 425 citations

Medicine, Behavioral Sciences, Psychology +13

The D1 dopamine receptor antagonist SCH 23390 increases cocaine self-administration in the rat

George F. Koob, Hoang Thai Le, Ian Creese · Neuroscience Letters · 1987 · 279 citations

Medicine, Neuroscience, Pharmacology +12