The synthesis and some chemical and spectroscopic properties of imidazo [1,2‐<i>a</i>] pyrazine

Abstract

Abstract The parent imidazo [1,2‐ a ] pyrazine was prepared and shown to undergo electrophilic bromination at C‐3, and base‐catalyzed H→D exchange at C‐3 and C‐5. The perchloro derivative of this ring system was prepared and it was established that nucleophilic substitution by methoxide ion occurs at C‐5 and C‐8. Pmr spectral data for all compounds are presented.