Science · 1991 · 185 citations · 27 references
Life SciencesGeneticsMolecular GeneticsCircadian RhythmsInsect GeneticsSpeciationCircadian Clock MechanismsCircadian Molecular MechanismsHorizontal Gene TransferMate ChoiceMolecular ClocksReproductive CyclesBiological ClocksChimeric Gene ConstructionClock-controlled GenesDrosophila ModelsMolecular Clock MechanismsTransgenic Drosophila
Drosophila males modulate the interpulse intervals produced during their courtship songs. These song cycles, which are altered by mutations in the clock gene period, exhibit a species-specific variation that facilitates mating. We have used chimeric period gene constructs from Drosophila melanogaster and Drosophila simulans in germline transformation experiments to map the genetic control of their song rhythm difference to a small segment of the amino acid encoding information within this gene.
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