The detection of proline isomerase activity in FK506-binding protein by two-dimensional 1H NMR exchange spectroscopy

Investigation of exchange processes by two-dimensional NMR spectroscopy

J. Jeener, Beat H. Meier, P. Bachmann et al. · The Journal of Chemical Physics · 1979 · 4.8K citations

Natural Sciences, Chemistry, Physics +17

Application of phase sensitive two-dimensional correlated spectroscopy (COSY) for measurements of 1H-1H spin-spin coupling constants in proteins

Dominique Marion, Kurt Wüthrich · Biochemical and Biophysical Research Communications · 1983 · 3.2K citations

Natural Sciences, Biochemistry, Chemistry +10

Cyclophilin and peptidyl-prolyl cis-trans isomerase are probably identical proteins

Günter Fischer, Brigitte Wittmann‐Liebold, Kurt Lang et al. · Nature · 1989 · 1.4K citations

Life Sciences, Biochemistry, Molecular Biology +5

A receptor for the immuno-suppressant FK506 is a cis–trans peptidyl-prolyl isomerase

Matthew W. Harding, David Uehling, Stuart L. Schreiber · Nature · 1989 · 1.4K citations

Medicine, Immunology, Pharmacology +8

FK-506, a novel immunosuppressant isolated from a Streptomyces. I. Fermentation, isolation, and physico-chemical and biological characteristics.

Toru Kino, Hiroshi Hatanaka, MICHISANE HASHIMOTO et al. · The Journal of Antibiotics · 1987 · 1.2K citations · Full text

Medicine, Biochemistry, Pharmacology +10