A phase I trial of SJG-136 (NSC#694501) in advanced solid tumors

Display and Analysis of Patterns of Differential Activity of Drugs Against Human Tumor Cell Lines: Development of Mean Graph and COMPARE Algorithm

Kenneth D. Paull, Robert H. Shoemaker, Louis Hodes et al. · JNCI Journal of the National Cancer Institute · 1989 · 969 citations

Medicine, Biostatistics, Oncology +16

Design, Synthesis, and Evaluation of a Novel Pyrrolobenzodiazepine DNA-Interactive Agent with Highly Efficient Cross-Linking Ability and Potent Cytotoxicity

Stephen J. Gregson, Philip W. Howard, John A. Hartley et al. · Journal of Medicinal Chemistry · 2001 · 200 citations

Pharmacy, Medicinal Chemistry, Pharmacology +17

SJG-136 (NSC 694501), a Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity

John A. Hartley, Victoria J. Spanswick, Natalie Brooks et al. · Cancer Research · 2004 · 137 citations

Medicine, Oncology, Pharmacology +15

Inhibition of Bacteriophage T7 RNA Polymerase <i>in </i><i>Vitro</i> Transcription by DNA-Binding Pyrrolo[2,1-<i>c</i>][1,4]benzodiazepines

Madhu S. Puvvada, Stephen A. Forrow, John A. Hartley et al. · Biochemistry · 1997 · 85 citations

Life Sciences, Molecular Biology, Pharmacology +10

SJG-136 (NSC 694501), A Novel Rationally Designed DNA Minor Groove Interstrand Cross-Linking Agent with Potent and Broad Spectrum Antitumor Activity

Michael C. Alley, Melinda G. Hollingshead, Christine Pacula-Cox et al. · Cancer Research · 2004 · 83 citations

Medicine, Oncology, Pharmacology +15