Orthogonal Glycosylation Strategy for Rapid Assembly of Oligosaccharides on a Polymer Support

Abstract

Only a single purification step is required to isolate the glycoconjugate-related oligosaccharides prepared by a new strategy, which is shown schematically below. Prior to purification the support-bound oligosaccharide, which is labeled with a hydrophobic tag, is cleaved from the polymeric support and deprotected.