Iridium-Catalyzed Asymmetric Hydrosilylation of Imines Using Chiral Oxazolinyl-Phosphine Ligands

Abstract

Chiral oxazolinylphosphines are effective ligands for the Ir(I)-catalyzed asymmetric hydrosilylation of imines to afford the corresponding sec-amines with high enantioselectivities (up to 89% ee) after hydrolysis in almost quantitative yields. The structure of an Ir(I)−oxazolinylferrocenylphosphine complex was determined by X-ray analysis.