Concepedia

Combination treatment of PKD utilizing dual inhibition of EGF-receptor activity and ligand bioavailability

William E. Sweeney, Kiyoshi Hamahira, Jennifer Sweeney, Michelle Garcia-Gatrell, Philip Frost, Ellis D. Avner

Kidney International · 2003 · 80 citations · 36 references

DOI

Concepts

References

36

An Essential Role for Ectodomain Shedding in Mammalian Development

Jacques J. Peschon, Jennifer L. Slack, P. Linga Reddy et al. · Science · 1998 · 1.6K citations

, , +10

<b> <i>PKD2</i> </b> , a Gene for Polycystic Kidney Disease That Encodes an Integral Membrane Protein

Toshio Mochizuki, Guanqing Wu, Tomohito Hayashi et al. · Science · 1996 · 1.4K citations

, , +17

The Polycystic Kidney Disease Proteins, Polycystin-1, Polycystin-2, Polaris, and Cystin, Are Co-Localized in Renal Cilia

Bradley K. Yoder, Xiaoying Hou, Lisa M. Guay‐Woodford · Journal of the American Society of Nephrology · 2002 · 939 citations

, , +16

The gene mutated in autosomal recessive polycystic kidney disease encodes a large, receptor-like protein

Christopher J. Ward, Marie C. Hogan, Sandro Rossetti et al. · Nature Genetics · 2002 · 763 citations

, , +14

Polycystic kidney disease: The complete structure of the PKD1 gene and its protein

Cell · 1995 · 619 citations · Full text

, , +12