BMJ · 1997 · 46 citations · 60 references
Veterinary MedicineInfectious DiseasesInternal MedicineClinical EpidemiologyEpidemiologyPulmonologyAge-period-cohort AnalysisBacterial InfectionsMortality AnalysisRespiratory DiseaseAge Group ClassificationAge-related Infection PatternsChlamydia Infection EpidemiologyObservational Study Analysis
Objective: To determine trends in asthma mortality by age group in England and Wales during 1983-95.Design: Observational study.Setting: England and Wales.Subjects: All deaths classified as having an underlying cause of asthma registered from 1 January 1983 to 31 December 1995.Main outcome measure: Time trends for age specific asthma deaths.Results: Deaths in the age group 5-14 years showed an irregular downward trend during 1983-95; deaths in the age groups 15-44, 45-64, and 65-74 years peaked before 1989 and then showed a downward trend; and deaths in the age group 75-84 years peaked between 1988 and 1993 and subsequently dropped.Trends were: age group 5-14 years, 6% (95% confidence interval 3% to 9%); 15-44 years, 6% (5% to 7%); 45-64 years, 5% (4% to 6%); 65-74 years, 2% (1% to 3%).Deaths in the 75-84 and 85 and over categories plateaued.Conclusions: There are downward trends in asthma mortality in Britain, which may be due to increased use of prophylactic treatment.
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Rapid turnover of plasma virions and CD4 lymphocytes in HIV-1 infection
David D. Ho, Avidan U. Neumann, Alan S. Perelson et al. · Nature · 1995 · 4.3K citations
Rapid method for measurement of bronchial responsiveness.
K Yan, Cheryl M. Salome, Ann J. Woolcock · Thorax · 1983 · 760 citations · Full text