Quantification of morphine, morphine 6-glucuronide, buprenorphine, and the enantiomers of methadone by enantioselective mass spectrometric chromatography in whole blood

Stereoselective Block of hERG Channel by (S)-Methadone and QT Interval Prolongation in CYP2B6 Slow Metabolizers

Chin B. Eap, Séverine Crettol, Jürg Schläpfer et al. · Clinical Pharmacology & Therapeutics · 2007 · 255 citations

Medicine, Pharmacokinetics, Pharmacology +15

Supervised injectable heroin or injectable methadone versus optimised oral methadone as treatment for chronic heroin addicts in England after persistent failure in orthodox treatment (RIOTT): a randomised trial

John Strang, Nicola Metrebian, Nicholas Lintzeris et al. · The Lancet · 2010 · 224 citations

Medicine, Pharmacology, Pharmacotherapy +11

The quantitative analysis of heroin, methadone and their metabolites and the simultaneous detection of cocaine, acetylcodeine and their metabolites in human plasma by high-performance liquid chromatography coupled with tandem mass spectrometry

Elisabeth J. Rook, M. J. X. Hillebrand, Hilde Rosing et al. · Journal of Chromatography B · 2005 · 136 citations

Pharmacy, Pharmacology, Toxicology +17

Determination of morphine and its 3- and 6-glucuronides, codeine, codeine-glucuronide and 6-monoacetylmorphine in body fluids by liquid chromatography atmospheric pressure chemical ionization mass spectrometry

M Bogusz, R. D. Maier, M Erkens · Journal of Chromatography B Biomedical Sciences and Applications · 1997 · 120 citations

Pharmacy, Pharmaceutical Analysis, Pharmacology +12

Fatal poisoning in drug addicts in the Nordic countries in 2007

Kirsten Wiese Simonsen, Per T. Normann, G. Ceder et al. · Forensic Science International · 2010 · 82 citations

Pharmacy, Pharmacology, Toxicology +16