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IMMUNIZING PROPERTIES OF ALLOGENEIC DENTAL PULP GRAFTS IN RABBITS
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References
1967
Year
Tissue EngineeringCell TherapyComposite AllograftImmunologyPathologyTissue TransplantationDermatologyRegenerative MedicineGraft SurvivalCell TransplantationXenotransplantationTransplantationOral CavityDental PulpDental Pulp TransplantationDental Pulp GraftingWound HealingMedicineGraft Rejection
It was established that allogeneic dental pulp grafts in rabbits evoke the delayed blastic reaction in regional lymph nodes. Accelerated rejection of skin grafts performed 3 weeks after dental pulp transplantation provided evidence for the immunizing properties of dental pulp. Osteodentin-like tissue found after dental pulp grafting was probably the result of cell growth and differentiation of the graft. This tissue is formed in normal as well as in the majority of preimmunized animals. The retardation of the blastic reaction and the resistance of dental pulp grafts to preimmunization may depend on the particular structure of the grafts, which may render more difficult the liberation of antigen and/or protect the graft from immunological attack.