Novel 12-membered non-antibiotic macrolides, EM900 series with anti-inflammatory and/or immunomodulatory activity; synthesis, structure–activity relationships and in vivo study

Macrolide antibiotics. Chemistry, biology, and practice

A. Nagel · Journal of Pharmaceutical Sciences · 1985 · 478 citations

Pharmacy, Medicinal Chemistry, Pharmacology +12

Inhibition of leukotriene synthesis markedly accelerates healing in a rat model of inflammatory bowel disease

John L. Wallace, Wallace K. MacNaughton, Gerald P. Morris et al. · Gastroenterology · 1989 · 433 citations · Full text

Veterinary Medicine, Pathobiology, Pharmacology +16

Erythromycin mimics exogenous motilin in gastrointestinal contractile activity in the dog

Zen Itoh, Mitsuo Nakaya, T Suzuki et al. · American Journal of Physiology-Gastrointestinal and Liver Physiology · 1984 · 297 citations

Medicine, Pharmacology, Physiology +15

[Clinical effects of low-dose long-term erythromycin chemotherapy on diffuse panbronchiolitis].

Shoji Kudoh, Takeshi Uetake, Kouich Hagiwara et al. · PubMed · 1987 · 229 citations

Medicine, Pharmacology, Pharmacotherapy +3

Macrolides with gastrointestinal motor stimulating activity

Satoshi Ōmura, Kazuo Tsuzuki, Toshiaki Sunazuka et al. · Journal of Medicinal Chemistry · 1987 · 175 citations

Pharmacy, Medicinal Chemistry, Pharmacology +7