Effects of nitroglycerin at therapeutic doses on platelet aggregation in unstable angina pectoris and acute myocardial infarction

Mechanism of vascular smooth muscle relaxation by organic nitrates, nitrites, nitroprusside and nitric oxide: evidence for the involvement of S-nitrosothiols as active intermediates.

L J Ignarro, Howard Lippton, Jo C. W. Edwards et al. · Journal of Pharmacology and Experimental Therapeutics · 1981 · 1.6K citations

Life Sciences, Biophysics, Physiology +6

Agonist-induced endothelium-dependent relaxation in rat thoracic aorta may be mediated through cGMP.

Robert M. Rapoport, Ferid Murad · Circulation Research · 1983 · 933 citations · Full text

Medicine, Pharmacology, Physiology +12

The electronic aggregometer: A novel device for assessing platelet behavior in blood

David C. Cardinal, Roderick J. Flower · Journal of Pharmacological Methods · 1980 · 699 citations

Medicine, Bioengineering, Hematology +16

The mechanisms of nitroglycerin action: stenosis vasodilatation as a major component of the drug response.

B G Brown, Edward L. Bolson, Robert B. Petersen et al. · Circulation · 1981 · 461 citations

Medicine, Cardiology, Pharmacology +16

Biochemical evidence of a chronic abnormality in platelet and vascular function in healthy individuals who smoke cigarettes.

Jacek Nowak, John Murray, John A. Oates et al. · Circulation · 1987 · 385 citations · Full text

Medicine, Geriatric Medicine, Surgery +14