The contribution of Notch1 to nephron segmentation in the developing kidney is revealed in a sensitized Notch2 background and can be augmented by reducing Mint dosage

Mutations in NOTCH1 cause aortic valve disease

Vidu Garg, Alecia N. Muth, J. Ransom et al. · Nature · 2005 · 1.5K citations

Medicine, Genetics, Molecular Genetics +12

Notch signaling is essential for vascular morphogenesis in mice

Luke T. Krebs, Yingzi Xue, Christine R. Norton et al. · Genes & Development · 2000 · 1.1K citations · Full text

Life Sciences, Developmental Biology, Genetics +15

Six2 Defines and Regulates a Multipotent Self-Renewing Nephron Progenitor Population throughout Mammalian Kidney Development

Akio Kobayashi, M. Todd Valerius, Joshua W. Mugford et al. · Cell stem cell · 2008 · 975 citations · Full text

Life Sciences, Cell Biology, Developmental Biology +15

Intrinsic Epithelial Cells Repair the Kidney after Injury

Benjamin D. Humphreys, M. Todd Valerius, Akio Kobayashi et al. · Cell stem cell · 2008 · 867 citations · Full text

Medicine, Cell Biology, Nephrology +12

Notch signaling is a direct determinant of keratinocyte growth arrest and entry into differentiation

Annapoorni Rangarajan, Claudio Talora, Ryuhei Okuyama et al. · The EMBO Journal · 2001 · 860 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +10