Concepedia

Myeloid-Derived Suppressor Cells as an Immune Parameter in Patients with Concurrent Sunitinib and Stereotactic Body Radiotherapy

Hui-Ming Chen, Ge Ma, Neil Gildener‐Leapman, Samuel Eisenstein, Brian A. Coakley, Junko Ozao, John Mandeli, Celia M. Divino, Myron Schwartz, Max W. Sung,

Clinical Cancer Research · 2015 · 102 citations · 42 references

DOIFull text

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Abstract

Sunitinib treatment increased the efficacy of SBRT in patients with oligometastases by reversing MDSC and Treg-mediated immune suppression and may enhance cancer immune therapy to prevent tumor recurrence post-SBRT.

References

42

Immunologic Correlates of the Abscopal Effect in a Patient with Melanoma

Michael A. Postow, Margaret K. Callahan, Christopher A. Barker et al. · New England Journal of Medicine · 2012 · 2K citations · Full text

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Gr-1+CD115+ Immature Myeloid Suppressor Cells Mediate the Development of Tumor-Induced T Regulatory Cells and T-Cell Anergy in Tumor-Bearing Host

Bo Huang, Ping‐Ying Pan, Qingsheng Li et al. · Cancer Research · 2006 · 1.4K citations

Increased circulating myeloid-derived suppressor cells correlate with clinical cancer stage, metastatic tumor burden, and doxorubicin–cyclophosphamide chemotherapy

C. Marcela Díaz‐Montero, Mohamed L. Salem, Michael I. Nishimura et al. · Cancer Immunology Immunotherapy · 2008 · 1.2K citations

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Clinical Impact of Different Classes of Infiltrating T Cytotoxic and Helper Cells (Th1, Th2, Treg, Th17) in Patients with Colorectal Cancer

Marie Tosolini, Amos Kirilovsky, Bernhard Mlecnik et al. · Cancer Research · 2011 · 1.1K citations

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The Proinflammatory CD14+CD16+DR++ Monocytes Are a Major Source of TNF

Kai-Uwe Belge, Farshid Dayyani, Alexia Horelt et al. · The Journal of Immunology · 2002 · 873 citations · Full text

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