Analysis and modeling of swelling and erosion behavior for pure HPMC tablet

HPMC-Matrices for Controlled Drug Delivery: A New Model Combining Diffusion, Swelling, and Dissolution Mechanisms and Predicting the Release Kinetics

Juergen Siepmann, H. Kranz, Roland Bodmeier et al. · Pharmaceutical Research · 1999 · 362 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate

Ruggero Bettini, Pier Luigi Catellani, Patrizia Santi et al. · Journal of Controlled Release · 2001 · 235 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Hydrophilic Matrices for Controlled Drug Delivery: An Improved Mathematical Model to Predict the Resulting Drug Release Kinetics (the “sequential Layer” Model)

Juergen Siepmann · Pharmaceutical Research · 2000 · 221 citations

Pharmacy, Pharmaceutics, Pharmacokinetics +17

Observation of swelling process and diffusion front position during swelling in hydroxypropyl methyl cellulose (HPMC) matrices containing a soluble drug

Paolo Colombo, Ruggero Bettini, Nikolaos A. Peppas · Journal of Controlled Release · 1999 · 218 citations

Pharmacy, Pharmaceutics, Drug Delivery +14

A New Model Describing the Swelling and Drug Release Kinetics from Hydroxypropyl Methylcellulose Tablets

Juergen Siepmann, Kairali Podual, Mongkol Sriwongjanya et al. · Journal of Pharmaceutical Sciences · 1999 · 184 citations

Pharmacy, Pharmaceutics, Bioavailability +15