Translocation of drug particles in HPMC matrix gel layer: effect of drug solubility and influence on release rate

Controlled Release of a Luteinizing Hormone-Releasing Hormone Analogue from Poly(d,l-lactide—co-glycolide) Microspheres

Lynda M. Sanders, John S. Kent, G.I. McRae et al. · Journal of Pharmaceutical Sciences · 1984 · 251 citations

Pharmacy, Endocrinology, Pharmaceutics +16

Analysis of the swelling and release mechanisms from drug delivery systems with emphasis on drug solubility and water transport

Paolo Colombo, Ruggero Bettini, Patrizia Santi et al. · Journal of Controlled Release · 1996 · 251 citations

Pharmacy, Molecular Pharmaceutics, Pharmaceutics +17

Drug diffusion front movement is important in drug release control from swellable matrix tablets

Paolo Colombo, Ruggero Bettini, Gina Massimo et al. · Journal of Pharmaceutical Sciences · 1995 · 222 citations

Pharmacy, Pharmaceutics, Controlled Release Formulations +15

Swelling and drug release in hydrogel matrices: polymer viscosity and matrix porosity effects

Ruggero Bettini, Paolo Colombo, Gina Massimo et al. · European Journal of Pharmaceutical Sciences · 1994 · 164 citations

Natural Sciences, Materials Science, Pharmaceutics +17

Structure and behaviour in hydrophilic matrix sustained release dosage forms: 2. NMR-imaging studies of dimensional changes in the gel layer and core of HPMC tablets undergoing hydration

Ali R. Rajabi‐Siahboomi, Richard Bowtell, P. Mansfield et al. · Journal of Controlled Release · 1994 · 157 citations

Pharmacy, Pharmaceutical Analysis, Pharmaceutics +17