A New Antifouling Hexapeptide from a Palauan Sponge, <i>Haliclona </i>sp.

Yutaka Sera, Kyoko Adachi, Kiyonaga Fujii, Yoshikazu Shizuri

Journal of Natural Products · 2003 · 44 citations · 8 references

Concepts

Abstract

Bioassay-guided fractionation of an extract of the sponge Haliclona sp. provided a known hexapeptide, waiakeamide (1), and a new sulfone derivative (2). The structures of hexapeptides 1 and 2 were elucidated by extensive NMR analyses and the advanced Marfey's method with LC/MS. These compounds showed repellent activity against the blue mussel, Mytilus edulis galloprovincialis.

References

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