Richard J. Clark

The Engineering of an Orally Active Conotoxin for the Treatment of Neuropathic Pain

Richard J. Clark, Jonas E. Jensen, Simon T. Nevin et al. · Angewandte Chemie International Edition · 2010 · 311 citations

Microcin J25 Has a Threaded Sidechain-to-Backbone Ring Structure and Not a Head-to-Tail Cyclized Backbone

K. Johan Rosengren, Richard J. Clark, Norelle L. Daly et al. · Journal of the American Chemical Society · 2003 · 261 citations

Engineering stable peptide toxins by means of backbone cyclization: Stabilization of the α-conotoxin MII

Richard J. Clark, Harald Fischer, L. Dempster et al. · Proceedings of the National Academy of Sciences · 2005 · 226 citations · Full text

Toxinology, Peptide Engineering, Backbone Cyclization +25

Engineering pro-angiogenic peptides using stable, disulfide-rich cyclic scaffolds

Lai Yue Chan, Sunithi Gunasekera, Sónia Troeira Henriques et al. · Blood · 2011 · 202 citations · Full text

Engineering Stabilized Vascular Endothelial Growth Factor-A Antagonists: Synthesis, Structural Characterization, and Bioactivity of Grafted Analogues of Cyclotides

Sunithi Gunasekera, Fiona Foley, Richard J. Clark et al. · Journal of Medicinal Chemistry · 2008 · 179 citations

Structural Characterization, Engineering, Grafted Analogues +17