Paeoniflorin reduced acute toxicity of aconitine in rats is associated with the pharmacokinetic alteration of aconitine

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Pharmacy, Pharmaceutical Analysis, Pharmaceutics +14

Mechanisms Responsible for Poor Oral Bioavailability of Paeoniflorin: Role of Intestinal Disposition and Interactions with Sinomenine

Zhong Qiu Liu, Zhi‐Hong Jiang, Liang Liu et al. · Pharmaceutical Research · 2006 · 116 citations

Pharmacy, Pharmacokinetics, Pharmacology +13

Detection and validated quantification of toxic alkaloids in human blood plasma—comparison of LC‐APCI‐MS with LC‐ESI‐MS/MS

Jochen Beyer, Frank T. Peters, Hans H. Maurer · Journal of Mass Spectrometry · 2007 · 99 citations

Pharmacy, Pharmacology, Toxicology +17

Effects of long-term administrations of aconitine on electrocardiogram and tissue concentrations of aconitine and its metabolites in mice

Kentaro Wada, Makoto Nihira, Hideyuki Hayakawa et al. · Forensic Science International · 2004 · 87 citations

Medicine, Cardiology, Pharmacology +8

Effects of diammonium glycyrrhizinate on the pharmacokinetics of aconitine in rats and the potential mechanism

L. Chen, Jin Yang, Andrew K. Davey et al. · Xenobiotica · 2009 · 76 citations

Medicine, Pharmacokinetics, Pharmacology +3